Bone tired

时间:2019-03-06 01:13:01166网络整理admin

THE debilitating joint disease osteoarthritis may be caused by the failure of the powerhouses in cartilage cells, says Robert Terkeltaub of the Veterans Affairs San Diego Health System in California. Previous research had suggested that osteoarthritic cartilage contains increased levels of the free radical gas nitric oxide, which can interfere with mitochondria—the energy-producing organelles in cells. So Terkeltaub and his colleagues treated cartilage cells with compounds that hamper energy production. The cells took on features similar to osteoarthritic cartilage cells (Arthritis and Rheumatism, vol 43,