The frozen cells that heal sick livers

时间:2019-03-07 08:19:05166网络整理admin

By Nell Boyce PEOPLE with liver failure, who may die while waiting for a liver transplant, now have a lifeline. Scientists have discovered that frozen liver cells can keep patients alive until a suitable donor organ is available. The scientists salvaged healthy liver cells from donated organs that were unsuitable for whole-organ transplants because of damage to blood vessels or bile ducts, and froze them using liquid nitrogen. They then infused the cells into the livers or spleens of patients who were close to death from liver failure. Seven out of 12 patients who received the treatment at the Medical College of Virginia in Richmond lived long enough to have a whole-organ liver transplant. One woman with acute liver failure resulting from a painkiller overdose made a full recovery with the cells alone. “She’s like a miracle,” says Jaime Tisnado, who presented his team’s results this week at a meeting of the Radiological Society of North America in Chicago. “We’re still in this semi-experimental stage but it definitely works.” Doctors at the University of Nebraska Medical Center have successfully used liver cell infusions to treat two children with potentially fatal genetic liver defects. One infant who was diagnosed with a liver disorder whilst still in the womb was given repeated liver cell infusions immediately after birth. The child survived for five months,